Osteoporosis literally means porous bones, but is defined as medical condition where bones become weak and brittle, resulting in bone loss. Physiologically speaking, it is a symptom of impaired bone and calcium metabolism, which is just one of the many symptoms of impaired energy metabolism.
The Physiology of Bone Loss
When calcium enters a de-energized cell (usually from stress, aging and hypothyroid), it triggers a series of reactions that further lower energy production, mainly by impairing oxidative metabolism.
In general, both calcium and iron accumulate in the aging body; they both have affinity for similar locations and they both displace copper - removing it from important locations and putting it into soft tissues, causing the loss of hair color, age spots.
When calcium and iron accumulate, they displace copper and cause it to bind with elastin, a major protein that makes up tissues like skin and arteries. When this happens, the elastin starts to calcify; resulting in things like calcified scalp tissue in baldness and hard arteries.
When the metabolism is working efficiently (via good thyroid function) and the mitochondria are functioning properly they produce carbon dioxide and bicarbonate, which are reasonable for outward flow and elimination of calcium from the mitochondria.
However, when the mitochondria damaged from oxidative stress (hypothyroidism), they are known to start the process of pathological calcification, where soft tissues become calcified and hard tissues like bones loss their calcium. And since healthy mitochondrial and thyroid function are responsible for producing carbon dioxide, and for keeping calcium outside the cell, an efficient defense system against osteoporosis would involve some form of pro-thyroid therapy.
In fact, in one study done on "hyperthyroid" rats, it was found that the mice who produced abundance of carbon dioxide had accelerated bone formation. This implies the pro-bone effects of carbon dioxide. Carbonate also happens to be present in newly formed bones.
Additionally, ATP is thought to be the most important substance governing protein formations. The greatest amount of ATP as well as CO2 happen to both be produced under thyroid-driven metabolism.
True Causes of Bone Loss
So far, in a nutshell, it is impaired oxidative energy metabolism that causes bone loss by inverting calcium metabolism. In other words, when our cells do not produce enough energy, they pull in calcium, rather than deposit it into the hard tissues.
One of the key players in this state is elevated levels of estrogen. Estrogen increases during stress and hypothyroidism, which is otherwise opposed by thyroid hormone. It leads to bone loss by causing an increased secretion of prolactin and the glucocorticoids (cortisol, etc), all which cause bone loss by robbing the hard tissues (bones and teeth) of calcium to use during stress.
Prolactin attributes to bone loss by catabolizing the bone, stealing calcium from the bones. You can lower prolactin significantly by improving thyroid function and using herbs like Ashwagandha, Black Ant (zinc) and Mucuna Pruriens.
Serotonin is another contributing factor to bone loss. In fact, studies have confirmed that the use of selective serotonin reuptake inhibitors (SSRIs) during lactation was associated with excessive, irreversible bone loss in mice. 1
*Taking high doses of folic acid and anti-serotonin herbs like Gingko Biloba can help to reduce bone loss by limiting serotonin's action.
Natural Cures for Osteoporosis
Improve Thyroid and Progesterone Levels: unlike estrogen, not only oppose the calcium-robbing prolactin and parathyroid, they direct encourage bone-building, and are associated with a decreased risk of cancer, aging and disease. Therefore, either supplementing a desiccated thyroid and/or natural progesterone would be wise for their general anti-aging effects, and specific protective qualities on the bones.
Pro-tip* the classic stress hormone cortisol is a great inhibit of both thyroid and progesterone. when cortisol is high, it "steals" pregnenolone, inhibiting progesterone production. cortisol also triggers the secretion of estrogen, which opposes thyroid on cellular level. therefore, utilizing anti-cortisol herbs like Ashwagandha and Ginkgo Biloba would prove therapeutic.
DHEA: The mother hormone is powerfully stimulatory on bone formation, like thyroid and progesterone, it is pro-metabolic, stimulating oxidative metabolism. In study, pigs with hyperthermia (indicating low thyroid) there is slow removal of calcium from the contractile apparatus of their muscles. This indicates that carbon dioxide production is poor, suggesting hypothyroid. DHEA; however, can help correct this similarly to how thyroid and progesterone would.
Pro-tip* do not supplement DHEA if you have hypothyroid, as the absence of thyroid can result in DHEA turning into cortisol and estrogen. Be sure to boost thyroid function with herbs like Ashwaganhda and desiccated thyroid first.
Magnesium: In addition to carbonate, magnesium is a component of newly formed bone. The best source of magnesium seems to be organic coffee and cacao.
Avoid PUFA: The avoidance of polyunsaturated vegetable fats/oils is important for protecting oxidative metabolism. PUFA are the building blocks for inflammatory prostaglandins, which have been implicated in osteoporosis. But perhaps more importantly, they inhibit good thyroid function and can directly interfere with calcium metabolism by increasing estrogen and prolactin.
Ultimately, osteoporosis is the result of a broken metabolism, which increases the calcification of soft tissues, decreasing the calcification of bones, and leading to the dengerateon of the body.
Fortunately, the combination of supplements of desiccated thyroid, magnesium, progesterone and DHEA can usually restore normal metabolic and thyroid function, whichwoul denture normalize calcium metabolism.
LastlThe avoidance of polyunsaturated vegetable oils is important for protecting respiration; some of the prostaglandins they produce have been implicated in osteoporosis, but more generally, they antagonize thyroid function and they can interfere with calcium control. The presence of the "Mead acid" (the omega-9 unsaturated fat our enzymes synthesize) in cartilage suggests a new line of investigation regarding the bone-toxicity of the polyunsaturated dietary oils.